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Rss feeds ⻠sitewide | earth | heavens | body | brain | culture| technology home earth heavens body brain culture tech the protein apc slows lou gehrig's disease in mice posted on: october 19, 2009 - 9:30pm tweet amyotrophic lateral sclerosis (als), also known as lou gehrig's disease, is a neurodegenerative disease that causes progressive weakness, disability, and death. canada pharmacy viagra Treatments are largely palliative. buy viagra next day delivery uk Using mice carrying the mutated form of the human sod1 gene that causes inherited forms of als, however, berislav zlokovic and colleagues, at the university of rochester medical center, rochester, have now found that administration of the protein apc slows disease progression and extends survival. viagra uk forum The authors therefore suggest that strategies designed to activate apc might be of benefit to patients with inherited, and possibly sporadic, als. viagra soft tab review However, in an accompanying commentary, charles esmon and jonathan glass warn that such an approach would not be without risks. viagra uk forum In the study, administration of both apc, whose main function is to prevent blood clotting, and apc analogs with a reduced ability to prevent blood clotting slowed disease progression in the mutant sod1–expressing mice and extended their survival, even when the compounds were administered after disease onset. cheap viagra without a prescription Further analysis indicated that these compounds were able to access the brain and that once there, they worked by decreasing expression of the mutant sod1 in several cell types in the brain, including the nerve cells destroyed in individuals with als. generic viagra This study therefore indicates that apc can have a neuroprotective effect in mouse models of inherited als. buy generic viagra online Source: journal of clinical investigation post new comment your name: * e-mail: * the content of this field is kept private and will not be shown publicly. viagra cost in canada Homepage: comment: * allowed html tags:


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